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In 3 we learned that some tissues, particularly the brain, red blood cells, and the renal medulla, depend heavily on glycolysis to satisfy their ATP needs. Yet, as discussed in 8, the glycogen stores of the body are limited and provide only about an 8- tol0-hour supply of glucose to maintain the plasma glucose concentration within normal limits. Gluconeogenesis is the process by which the body synthesizes glucose from endogenous noncarbohydrate precursors, primarily lactate and glycerol, and the carbon skeletons of the amino acids alanine and glutamine. This pathway is essential for maintaining the concentration of blood glucose in the fasted state. The term g k o neogenesis is used to indicate that this process is explicitly distinct from the interconversion of hexose sugars, through which glucose is generated from dietary fructose or galactose. Unlike other fuel sources such as amino acids, lactate, and glycerol, the carbon skeletons of most fatty acids cannot be utilized for gluconeogenesis. Virtually all physiological fatty acids contain an even numbers of carbons (usually, C16 or C18) and their catabolism involves cleavage of the fatty acid chain into two-carbon acetylCoA units. Humans and other animals lack a pathway for converting acetyl-CoA to glucose. On the other hand, the oxidation of the relatively rare odd-chain fatty acids and branched methyl fatty acids that are present in human diets do generate small amounts of propionic acid that can be converted into glucose.

junk food I have found that most temptations are better avoided than resisted I ve noticed that some hotels no longer have mini bars, but instead they lay the food out on top of a table Thus, the don t get the key defense doesn t work In such cases, I call down to the front desk and have them remove the food I once arrived at one such devious hotel so late at night that I wanted to go to sleep immediately and not wait for someone to remove the food As a partial preventative measure, I put a towel over the chocolate bars and other treats While I still knew the junk food was in my room, at least I couldn t see it As we have seen, our investing instincts are out of sync with market opportunity.

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The investments that feel good are precisely those that are most likely to cost us money, and vice versa This leads to the paradoxical situation that we sometimes gain by having fewer options Usually, having more options is better, but when our instincts lead us to bad choices as with junk food in the mini bar or with emotional investing decisions we can make ourselves better off precisely by limiting our alternatives This less or more insight into self-control has become closely associated with the story of Odysseus and the Sirens On his way home from the Trojan War, Odysseus had to sail past the Island of Sirens These maidens song was so beautiful that sailors approached them and were killed as their ships crashed on the rocks surrounding the island.

The goddess Circe warns Odysseus of the danger and provides him with a solution in this passage of The Odyssey: If any one unwarily draws in too close and hears the singing of the Sirens, his wife and children will never welcome him home again, for they sit in a green field and warble him to death with the sweetness of their song but if you like you can listen yourself, for you may get the men to bind you as you stand upright on a cross-piece half way up the mast, and they must lash the rope s ends to the mast.

Rather than handling their own server computers, many corporations are relying on outside out ts to manage their technology at remote data centers, which pipe data to their premises via the Web. According to Hamm (2001), this piping technology arrangement can cut a company s computing cost by 15 to 20 percent. Data centers are operated by a third party, such as application service providers (ASPs) (see s 13 and 14). Major software vendors including IBM and SAP are in this business. For details on storage networks, see Technology Guide 3.

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ers (review Figure 2-7). These headers are transmitted along with the data inside the Data Link Layer frame (Figure 2-15). The information to be transmitted originates at the Application Layer, and is therefore called Application Data (AD). The Application Header (AH) is then appended to the data, and that combination (AH + AD) is passed to the next lowest layer (e.g. the Presentation Layer). The Presentation Layer treats this information (AH + AD) as its data, and appends its header (the Presentation Header or PH). The result is PH + AH + AD. This process continues until the entire frame is constructed with the appropriate PCI from each layer. The protocol analyzer s job can be defined simply: unravel all of the PCI and display it in a user-understandable format. As we will see from the case studies in this text, this process of unraveling is much more complex than it may initially appear, as both LAN and WAN elements are typically involved (Figure 2- 16).

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